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4. This image shows a graphical display how opioids inhibit overall nerve activi

ID: 263310 • Letter: 4

Question

4. This image shows a graphical display how opioids inhibit overall nerve activity. Which explanation fits best for box C?

A. Presynaptic inhibition—receptors activate a G protein that opens K+ channels to hyperpolarize the postsynaptic cells, reducing firing rate

B. Axoaxonic inhibition—receptors activate G proteins that close Ca2+ channels, reducing the release of neurotransmitter.

C. Presynaptic autoreceptors activate G proteins and reduce release of a co-localized neurotransmitter

D. Postsynaptic autoreceptors activate G proteins and reduce release of a co-localized neurotransmitter

Neuron with co-localind neurotransmutter and opioid Opioid ncuron Opioid neufon

Explanation / Answer

4. This image shows a graphical display how opioids inhibit overall nerve activi

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