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? -Aminobutyric acid (GABA) is a neurotransmitter that is released into the syna

ID: 263100 • Letter: #

Question

? -Aminobutyric acid (GABA) is a neurotransmitter that is released into the synaptic cleft during a nerve impulse. After the nerve impulse the GABA must be re-absorbed into the nerve cell to terminate transmission of the impulse. The re-uptake is accomplished by a Na-GABA symporter, which cotransports 3 Na+ for each GABA molecule. If the resting membrane potential is -60 mV (inside negative), the Na+ concentration outside the cell is 150 mM and 10 mM inside the cell, and the temperature is 37 °C, what is the maximum concentration gradient of GABA that can be achieved?

Explanation / Answer

? -Aminobutyric acid (GABA) is a neurotransmitter that is released into the syna

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