ote whether the following mutations are likely (based on their nature and locati

Question

ote whether the following mutations are likely (based on their nature and location) to result in either a significant to complete loss of protein function (SC); or a partial to negligible loss of protein function (PN). (5 Points) A) Deletion of 2 base pairs just downstream of the start codon B) Nonsense mutation in the second of fifteen exons. C) Transposon insertion in the 3' UTR. D) Missense mutation in a region of the gene that is required for proper folding/function of the protein. E) Silent mutation in a region of a gene that contains a conserved domain. F) Deletion of 3 base pairs just upstream of the stop codon. G) Transversion in the first intron. H) Frameshift mutation in the middle of a gene. Il) Temperature-sensitive mutation J) Deletion of the promoter

Explanation / Answer

A) Deletion of 2 base pairs just downstream of start Codon : SC

B) PN

C) PN

D) SN

E) PN

F) PN

G) PN

H) PN

I) PN

J) SN

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