Question 5 4 pts The production of heteroduplex DNA (regions where single strand

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Question 5 4 pts The production of heteroduplex DNA (regions where single strands from opposing homologs are base-paired with one another) during meiotic recombination results in occasional mispairing due to allelic differences between the two homologs. The example below shows the four results in a region of mispaired heteroduplex DNA. a) What will be the ratio of resulting alleles if the "G" in the second allele is corrected to a "T", and the "G" from the third allele is corrected to an "A"? b) What is this phenomenon called? A-A C- ?x'

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Answer a: According to the information, the original sequence for the DNA duplex is AACC/TGTG. After mutation, this sequence changes to AACC/TTAG. Thus, this will result in a mismatch of the DNA since C does not bind with A in the DNA. Thus, the allelic content after this mismatch would be AA_C and TT_G.

Answer b: These mutational changes where a purine is replaced with a pyrimidine (G to T) and a purine is changed with a purine are called transversion and transition mutations, respectively.

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