consider an artificial cell with: 100mM NaCl and 15mM KCl dissolved outside the

Question

consider an artificial cell with:

100mM NaCl and 15mM KCl dissolved outside the cell.  

10mM NaCl and 150mM KCl dissolved inside the cell.

What is the membrane potential when only potassium channels in the cell membrane are open?

A.

+124mV

B.

+62mV

C.

0mV

D.

-62mV

E.

-124mV

consider an artificial cell with:

100mM NaCl and 15mM KCl dissolved outside the cell.

10mM NaCl and 150mM KCl dissolved inside the cell.

Given your knowledge that membrane potential is proportional to the relative permeability of ion channels, what would you predict the membrane potential to roughly be if sodium channels open such that the membrane is 5x more permeable to sodium than potassium. Any other channels (e.g. chloride) remain closed.

A.

+62mV

B.

+30mV

C.

0

D.

-30mV

E.

-62mV

Explanation / Answer

1) When only the potassium channel is opened the membrane potential will be equal to - 62mV where inside it will have more potassium rather than outside and outside more positive in comparison to inside...

2) The membrane potential will be +30mV when the sodium ions open sodium influx occurs resulting in the change of the membrane potential..!!

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