Fill in the blank - I did not get a answer/key code for this question so I would

Question

Fill in the blank - I did not get a answer/key code for this question so I would like a professional/expert opinion on how to go about this.

DNA can be damaged in a number of ways. For example, depuriantion is the hydrolysis of _____________ bonds between _____________ and _______________ groups. This type of damage can be repaired by cutting out that abasic nulceotide from the backbone with ____________ (enzyme), filling in the gap with DNA Polymerase _____________ (bacteria), or _____________ (eukaryotes), and then ligating the new nucleotide to the backbone with ___________ (enzyme), which forms a ___________ bond.

Explanation / Answer

DNA can be damaged in a number of ways. For example, depurination is the hydrolysis of GLYCOSIDIC bonds between SUGAR and NITROGEN-BASE groups. This type of damage can be repaired by cutting out that abasic nucleotide from the backbone with AP ENDONUCLEASE and PHOSPHODIESTERASE (enzyme), filling in the gap with DNA Polymerase I (bacteria), or POLYMERASE ? (eukaryotes), and then ligating the new nucleotide to the backbone with DNA LIGASE (enzyme), which forms a PHOSPHODIESTER bond.

Related Questions

Navigate

• Browse (All)
• Browse F
• Subjects

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.