Growth fractions for two different types of tumors originating from epilthelial

Question

Growth fractions for two different types of tumors originating from epilthelial and embryonic cells were analyzed. The epithelial tumor growth factor of 75% while it was 50% for the embryonic tumor. The proliferation (P) and the quiescent (Q) for the two types of the cells are indicatted by P1/P2 and Q1/Q2, respectively. What is the relation between P and Q in this case?

a. Calculate P1/Q1 and P2/Q2 from the above given growth fractions.

b. If Q1 and Q2 are the same, then evaluate which of the two tumors has a higher proliferation?

*** EQUATION ***

Growth fraction (GF) = P / (P + Q)

There is no more information given, but let's assume that Q = 1000

Explanation / Answer

A. P1 = 75
q1 = 25

p1/q1 = 75/25 = 3

P2 = 50
q2 = 50

p2/q2 = 50/50 = 1

B. Q = 1000

P1 = 75% = 750
GF = 750/750+1000 = 750/1750 = 0.42

P2 = 50% = 500
GF = 500 / 500+1000 = 500/1500 = 0.33

epithelial tumor growth has high proliferation.

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