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1. Non-coding RNA processing a. Ribosomal RNA genes are expressed as polycistron

ID: 257150 • Letter: 1

Question

1.      Non-coding RNA processing

a.      Ribosomal RNA genes are expressed as polycistronic transcripts. What is a polycistronic transcript? What processing step is necessary to produce rRNAs from these transcripts?

b.      What is the C-glycoside isomer of uridine called? Why might this isomerization be common at uridine residues in highly structured RNAs?

c.       What steps are required for the processing of tRNA?

d.      What is the function of RNase P? What component carries out its catalytic mechanism?

Explanation / Answer

a.

b.

c.

d.

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