1. The strand of DNA used in Q12 problem undergoes another mutation, this time t

Question

1. The strand of DNA used in Q12 problem undergoes another mutation, this time the first G from the 5' end is changed to an A. The mutant template DNA is: 3' TACTAAACT 5'. What would change in the polypeptide?

A) No change

B) Polypeptide would be 1 amino acid shorter

C) Polypeptide would be 1 amino acid longer

D) 1 amino acid would substitute for another

E) Transcription would terminate within this stretch

2 )How many possible combinations of DNA sequences to code for a polypeptide consists of Glutamine – Proline – Cysteine?  

3. The template DNA sequence is 5’ ACCTGAGTC 3’, what is the transcribed mRNA sequence from 5’ to 3’??

Explanation / Answer

1- A

2- 16

3-5’ GACUCAGGU 3’

Note - there are two codon for glutamine 4 for proline and 2 for cysteine therefore 2x4x2 = 16

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