V X-Linked Inheritance 10. Hemophilia is the inability of the blood to properly

Question

V X-Linked Inheritance 10. Hemophilia is the inability of the blood to properly form clots. It is inherited as a recessive allele on the X chromosome. A man with a normal phenotype marriesa hemophilia allele (she has a normal phenotype but is heterozygous) A. What proportion of their daughters will have hemophilia? What proportion will be carriers? B. What proportion of their sons will have hemophilia? What proportion will be carriers? (Is it possible for a male to BE a carrier for an X-linked disorder?)

Explanation / Answer

Answer A) None of the daughters in their first generation will have hemophilia, however 50% of them will be carrier of the disease.

Answer B) 50% of their sons will be hemophilic, and none of them is carrier because male have only one X chromosome which will manifest the disease in males and becomes recessive in female making them as carrier of the disease.

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