7. Give the cellular localization(s) for each of the following respiration-relat

Question

7. Give the cellular localization(s) for each of the following respiration-related processes. If the location is within an organele, give the precise location within the organelle, e.g., mitochondrial intermembrane space or mitochondrial matrix. If the process occurs in more than one location, state all locations. (11 pts) initial activation step for fatty acid B-oxidation c) d) e) mitochondrial porins ethanol fermentation mito. pyruvate transporter glycerol metabolism substrate-level phosphorylation FADH2 synthesis electron transport chain (4 complexes) h) k) proton accumulation lactate dehydrogenase reduction of oxygen to water oxidative pentose phosphate pathway oxidation of NADH to NAD synthesis of acetyl Co-A from pyruvate GLUT transporter citric acid cycle NADPH synthesis CO2 evolution ATP synthase complex n) o) p) u)

Explanation / Answer

a) Glycolysis - Cytoplasm

b) Intial activation step of beta oxidation of fatty acid - Outer mitochondrial membrane

c) Mitochondrial porins - Outer mitochondrial membrane

d) Gluconeogenesis - Mitochondria or cytoplasm of liver or kidney cells

e) Ethanol fermentation - Cytoplasm

f) Mito. pyruvate transporter - Inner membrane of mitochondria

g) Glycerol metabolism - Cytoplasm

h) Substrate level phosphorylation - In the cytoplasm during glycolysis and inside mitochondrial matrix during krebs cycle.

i) FADH2 synthesis - in Mitochondrial matrix during krebs cycle

J) Electron transport chain - Inner mitochondrial membrane

k) Oxidative phosphorylation - Inner mitochondrial membrane.(cristae)

l) Proton accumulation - Intermembrane space of mitochondria

m) Lactate dehydrogenase- Outer membrane and periplasmic space of mitochondria

n) Reduction of oxygen to water - Inner mitochondrial membrane

o) Oxidative pentose phosphate pathway - Cytoplasm, In plants Plastids

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