43. In humans, Down Syndrome can result trom: a. three copies of chromosome 21 b

Question

43. In humans, Down Syndrome can result trom: a. three copies of chromosome 21 b. a translocation involving part of chromosome 21 and chromosome 14 c. a reciprocal translocation between any two autosomes d. a and b 44. It is possible to see human cases of aneuploidy in sex chromosomes (XO Turner syndrome and XXY Klinfelter syndrome) but not in autosomes. This is because a. X inactivation compensates for dosage of X chromosomes. b. XY chromosomes are more prone to nondisjunction and lagging in anaphase. c. humans have a gene that prevents the formation of monomic or trisomic type gametes. d. none of the above answers is correct. 45. During mitosis, if the chromosomes in a diploid tissue fail to separate after replication, the resulting daughter cells will be: a. monoploid b. tetrasomic c. triploid d. tetraploid

Explanation / Answer

43. A and B.

Down syndrome is also called Trisomy 21. It occurs due to presence of three copies of chromosome 21 in an individual. Down syndrome also occurs due to translocation of segments between chromosome 21 and 14 and it is called familial Down syndrome.

44. A. X inactivation compensates for dosage of X chromosomes.

45. C tetraploid.

If chromosomes in diploid cell fails to separate after replication, cell will be having 2 copies of each set of chromosomes and will thus tetraploid.

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