Sort the following statements into the appropriate bin, considering if they appl

Question

Sort the following statements into the appropriate bin, considering if they apply to competitive, uncompetitive, or mixed inhibitors. Items (7 items) (Drag and drop into the appropriate area below) Does not affect the Vmax of the reaction Does not bind to the active site of an enzyme, but can bind to the free enzyme or the enzyme- substrate complex Does not bind to the free enzyme Increasing inhibitor concentration decreases both the Vnax and the Km The y-axis intercept of the Lineweaver- Burk plot remains the same with or without this inhibitor Higher concentrationso substrate can reduce the effect of the inhibitor Binds to the active site of an enzyme

Explanation / Answer

Does not affect the Vmax of the reaction: Competitive inhibitors

Does not bind to free enzyme: Uncompetitive

Increasing inhibitor concentration decreases both Vmax and Km :Uncompetitive inhibitor

The y axis intercept of the line weaver- burk plot remains the same with or without this inhibitor: competitive inhibition

Higher concentrations of substrate can reduce the effect of the inhibitor: competitive inhibitor

Does not bind to the active site of the enzyme but can bind to the free enzyme or enzyme substrate complex: Mixed inhibitor

Binds to the active site of an enzyme: Competitive inhibitor

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