Which of the following statements best describes the clonal evolution of tumors?

Question

Which of the following statements best describes the clonal evolution of tumors? Environmental factors can contribute to a cell becoming cancerous, and these factors may interact with genetic predispositions to cancer. Tumor cells acquire more somatic mutations that allow them to become increasingly more aggressive in their proliferative properties. Tumor cells gain the ability to travel to other sites in the body, where they establish secondary tumors. If one or more of the required mutations is inherited, fewer additional mutations are required to produce cancer, and the cancer will tend to run in families. Both oncogenes and tumor-suppressor genes contribute to cancer but differ in their modes of action and dominance. Tumor-suppressor genes typically act in amanner, and oncogenes typically act in a manner O dominant, recessive O recessive; dominant O benign; malignant O benign; clonal O malignant, benign

Explanation / Answer

Answer:

Recessive; Dominant

Explanation:

Oncogenes promote cell proliferation, they act in a dominant manner. In contrast, mutations in tumor suppressor genes cause loss of function and act in a recessive manner.

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