Exam # 4 Grade/ Part 1: Multiple choice questions (70 peints) 1- Which of the fo

Question

Exam # 4 Grade/ Part 1: Multiple choice questions (70 peints) 1- Which of the following will cause a protein to stay in the cytosol after synthesis? a. Presence of an ER retention signal b. Presence of an ER signal peptide c Presence of a mitochondrial transit signal. d. Presence of a nuclear localization signal. e. Absence of a sorting signal. 2. If a protein contains a single internal start-transfer signal, it is most likely a. A secreted protein b. An integral membrane protein. c. A soluble ER protein. d. A cytosolic protein. e. None of the above 3- Protein destined to the are synthesized on free ribosomes a. Nucleus. b. Mitochondrion. c. Peroxisome. e. All of the above. 4 Outer and inner membrane translocases are needed to import proteins into the a. Nucleus b. Mitochondrion. c. Peroxisome. d. Chloroplast. e. b and d 5- All proteins destined to the are synthesized on ER-bound ribosomes a. Nucleus. b. Mitochondrion. c. Peroxisome d. Chloroplast e None of the above

Explanation / Answer

1) (E) sorting signals are signal on terminals of protein sequence that target them to their destined positions. Absence of these result in retention of proteins in the cytosol.

2) (B) internal start transfer signals are found in integral membrane proteins.

3) (E)

Proteins destined within the cell are synthesised in the free ribosomes.

4) (E)

Mitochondria and chloroplast share a similar mode of translocating proteins using an outer ans inner membrane translocators.

5) (E)

RER synthesis proteins that are translocated outside the cell.

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