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1. Combinatorial chemotherapeutic strategies utilized to treat neoplasms should

ID: 248865 • Letter: 1

Question

1. Combinatorial chemotherapeutic strategies utilized to treat neoplasms should include chemotherapy agents that have different mechanisms of action. (True or False) 2. The equilibrium dissociation constant used to quantitate drug interactions with receptors be defined as the concentration of free drug at which 100% of available receptors are occup can ie (True or False) 3. An individual who is considered to be an ultra rapid metabolizer has an activity score of zero. (True or False) 4. The sublingual route of administration is an enteral route by which a drug is absorbed into the blood stream through tissues under the tongue. (True or False) 5. Alzheimer's disease is due to a decrease in cholinergic neurons and can be treated with Tacrine. True or False) 6. Blood vessels and sweat glands are innervated by the parasympathetic nervous system alone (True or False).

Explanation / Answer

1. Correct answer:- True
Explanation:- combitarial chemotherapeutic agents are more effective than the single drug therapy, because these have different mechanism of action.

2. Correct answer:- False
Explanation:- Equilibrium dissociation constants only tells about affinity of the drug to its receptor.

3. Correct answer:- False
Explanation:- Activity Score accumulates throughout the day based on activities.
-Patients with a score >2.0 are classified as ultrarapid metabolizers.

4. Correct answer:- True
Explanation:- sublingual route of drug administration is entral beacause it occurs through mouth.

5. Correct answer:- True
Explanation:- Alzheimer's disease caused due to deficiency of cholinergic neurons.
- Tacrine is effective in Treatment.

6. Correct answer:- False
Explanation:- blood vessels and sweat gland innervated by both sympathetic and parasympathetic nervous system.