1. Determine the loading doses ( in mg) of tobramycin for a 72 year old male pat

Question

1. Determine the loading doses ( in mg) of tobramycin for a 72 year old male patient weighing 187 lb and measuring 5 ft 8 in in height with a serum creatinine of 2.8 mg/dL. The loading dose desired is 1.0 mg/kg of ideal body weight.

2. Determine the maintenance doses ( in mg every 8 hr) of tobramycin for a 72 year old male patient weighing 187 lb and measuring 5 ft 8 in in height with a serum creatinine of 2.8 mg/dL. For normal patient, 1.66 mg/kg of ideal body weight every 8 hours is used as the maintenance dose (adjusted for renal impairment).

3. If a serum sample is determined to contain 270 mg/dL of cholesterol, what is the concentration of cholesterol (MW 386) in terms of millimoles per liter.

Explanation / Answer

1.)52.3 mg tobramycin (loading dose)

2.)15.7 mg tobramycin (maintenance dose)

3.) 2700/386 = 7 millimoles per liter

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