1. Which CHA2DS2-VASc score suggests anticoagulant therapy is indicated? a. 1 or
ID: 240617 • Letter: 1
Question
1. Which CHA2DS2-VASc score suggests anticoagulant therapy is indicated?
a. 1 or more
b. 2 or more
c. 3 or more
d. 4 or more
2. What patient characteristics do the 2016 VTE treatment guidelines recommend for the use of NOACs over warfarin?
a. Lower extremity DVT in a patient with no cancer
b. Upper extremity DVT, recurrent and unprovoked
c. Patient with a proximal VTE, non-surgery related
d. Patient with a proximal VTE, surgery related
3. Which of the following anticoagulants is correctly listed with its major drug interaction pathway?
a. Warfarin: P-gp
b. Rivaroxaban: CYP2C9
c. Apixaban: CYP3A4 and P-gp
d. Dabigatran: CYP3A4
4. Which of the following oral anticoagulants in contraindicated in a patient with a CrCl of more than 95 mL/min?
a. Apixaban
b. Edoxaban
c. Dabigatran
d. Warfarin
Explanation / Answer
Q 1 Answer is B :
2 or more
Q. 2. Answer is A
in patients who experience DVT and do not have cancer
Q.3. Anser is A Warfarin and & pglycoprotien interaction
Q 4. Answer is B
Edoxaban is contraindicated in patients with CrCL >95 mL/min as it shows increased ischemic stroke.
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