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1. Which CHA2DS2-VASc score suggests anticoagulant therapy is indicated? a. 1 or

ID: 240617 • Letter: 1

Question

1. Which CHA2DS2-VASc score suggests anticoagulant therapy is indicated?

a. 1 or more

b. 2 or more

c. 3 or more

d. 4 or more


2. What patient characteristics do the 2016 VTE treatment guidelines recommend for the use of NOACs over warfarin?

a. Lower extremity DVT in a patient with no cancer

b. Upper extremity DVT, recurrent and unprovoked

c. Patient with a proximal VTE, non-surgery related

d. Patient with a proximal VTE, surgery related

3. Which of the following anticoagulants is correctly listed with its major drug interaction pathway?

a. Warfarin: P-gp

b. Rivaroxaban: CYP2C9

c. Apixaban: CYP3A4 and P-gp

d. Dabigatran: CYP3A4


4. Which of the following oral anticoagulants in contraindicated in a patient with a CrCl of more than 95 mL/min?

a. Apixaban

b. Edoxaban

c. Dabigatran

d. Warfarin

Explanation / Answer

Q 1 Answer is B :

2 or more

Q. 2. Answer is A

in  patients who experience DVT and do not have cancer

Q.3. Anser is A Warfarin and & pglycoprotien interaction

Q 4. Answer is B

Edoxaban is contraindicated in patients with CrCL >95 mL/min as it shows increased ischemic stroke.