3. Complete the table below. By ATP equivalents, I mean any deoxyribonucleotide

Question

3. Complete the table below. By ATP equivalents, I mean any deoxyribonucleotide or ribonucleotide (dATP, dCTP, dGTP, dTTP, or ATP are energetically equivalent).

Type of damage

Does it require? 1.no ATP or ATP equivalents,

2. a few ATP or ATP equivalents, or 3. many ATP or ATP equivalents

Does it require new DNA synthesis?

Repaired by which specific DNA repair system or systems?

Uncorrected mismatch from an error in DNA replication

UV-created thymine dimer

Alkylation of a base in DNA (non-bulky)

Loss of a base from DNA

Double-stranded break in DNA

Type of damage

Does it require? 1.no ATP or ATP equivalents,

2. a few ATP or ATP equivalents, or 3. many ATP or ATP equivalents

Does it require new DNA synthesis?

Repaired by which specific DNA repair system or systems?

Uncorrected mismatch from an error in DNA replication

UV-created thymine dimer

Alkylation of a base in DNA (non-bulky)

Loss of a base from DNA

Double-stranded break in DNA

Explanation / Answer

Ans.

Does it require? 1.no ATP or ATP equivalents,

2. a few ATP or ATP equivalents, or 3. many ATP or ATP equivalents

Type of damage

Does it require? 1.no ATP or ATP equivalents,

2. a few ATP or ATP equivalents, or 3. many ATP or ATP equivalents

Does it require new DNA synthesis? Repaired by which specific DNA repair system or systems? Uncorrected mismatch from an error in DNA replication 3 yes Mismatch repair UV-created thymine dimer 1 no photoreactivation repair by photoreactivation enzyme(PRE) Alkylation of a base in DNA (non-bulky) 2 no base excision repair Loss of a base from DNA 3 yes SOS repair Double-stranded break in DNA 3 yes double - strand break repair (homologous recombination repair or non-homologous end-joining)

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