4. A population is in mutation-selection balance for the adenoside deaminase def

Question

4. A population is in mutation-selection balance for the adenoside deaminase deficiency allele, d, which is recessive to the D allele at this locus. Individuals must be homozygous for the recessive d allele to have the disease. 1 in 8000 individuals have adenoside deaminase deficiency. Researchers determined that the mutation rate H of C to c is 10- What is the relative fitness (W) of individuals that are homozygous for the d allele? 5. A population of 100,000 Arahidapsis thaliana plants is initially at Hardy-Weinberg equilibrium for the A gene, where two alleles, Aj and A2, are present at equal frequencies. The population undergoes 2 generations of 100% self-fertilization. a) After 2 generations of selfing, what are the expected values for: 1) genotype frequencies, 2) allele frequencies, and 3) the population inbreeding coefficient. (The math is easiest using fractions.)

Explanation / Answer

Ans- according to question 1 in 8000 is born with disease.

The mutation rate is (10)5

So the relative fitness will be

8000/100000 = 0.08

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