1)Some antimicrobial drugs used to treat bacterial infections target the ribosom
ID: 219788 • Letter: 1
Question
1)Some antimicrobial drugs used to treat bacterial infections target the ribosome. Why is this a good target? Include in your answer what process is disrupted, what effect this has on the cell, and why these drugs do not hurt the human host.
2)Why does the production of beer and wine depend on the fermentative capabilities of microbes?
3)Current research is linking issues with splicing of mRNA to cancer cells in humans. Some cells are lacking in splicing ability while others are misdirecting the splicing, or over splicing. Why may under- or over-splicing cause issues within a eukaryotic cell?
4)Back in the 1930s, a chemical called DNP (2,4-Dinitrophenol) was prescribed as a weight loss pill. Describe how DNP is a metabolic poison and why it was thought to be a good mechanism for weight loss.
Explanation / Answer
Answer:
Most of the antibiotics stop the synthesis of protein in bacteria by interacting and inhibiting the function of the ribosome.
In human and bacteria ribosome is responsible for protein synthesis. The antibiotic drug like tetracycline cross through bacterial membrane and accumulate in the cytoplasm in high concentration. And block RNA interaction which eliminates protein chain lightning.
But in human level of concentration is not enough to terminate synthesis of protein.
Hence, it does not harm the humans.
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