Part D A dominant wild-type allele D produces full enzyme function, but a recess

Question

Part D A dominant wild-type allele D produces full enzyme function, but a recessive allele di produces no functional enzymatic action, and a recessive allele d2 produces reduced enzyme function. Western blot analysis of the proteins produced by organisms with different genotypes for this gene gives the results shown. Based on your assessment of the western blot analysis, speculate about the nature of the mutations producing di and d2. In other words, what has happened at the DNA level to produce these mutations? Select the four correct statements The mutation converting D to d2 could be a missense mutation that alters the splicing of pre-RNA. The mutation converting D to d1 could be a mutation that prevents translation of the RNA, such as a mutation in the start codon or Shine-Dalgarno sequence Genotype DD Dd Dd, dd, dd, dd The mutation converting D to d2 could be due to the presence of a premature stop codon resulting from either a nonsense mutation or a frameshift mutation. The mutation converting D to d1 could be a mutation that increases the lifetime of the RNA, such as a mutation in the polyadenylation site The mutation that converted D to d2 could be a mutation that prevents transcription of the gene, such as a promoter mutation. The mutation converting D to di could be a missense mutation that changes the protein's charge Submit Request Answer

Explanation / Answer

d1d1 = No protein produced = Option B
d2d2 = Truncated protein produced = Option A and C

For option D to be correct, the mutation in d1 could be DECREASING the lifetime of the RNA, such as a mutation in the polyadenylation site.

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