Telomeres are special chromosomal termini added by telomerase. How does telomera

Question

Telomeres are special chromosomal termini added by telomerase. How does telomerase add "fake" DNA to the ends of chromosomes? a) telomerase serves as a bridge that allows the replisome continue DNA synthesis beyond the end of the chromosome. b) telomerase is a ribozyme that contains RNA that serves as template for DNA polymerase to add non-sense repetitive DNA to the ends of linear chromosomes. c) telomerase binds to chromosome ends and synthesizes non-sense DNA extensions. d) telomerase contains RNA that is converted into DNA and added to the ends of chromosomes.

Explanation / Answer

Option b is the correct answer.

Telomerase is a ribozyme that contains RNA that serves as template for DNA polymerase to add non-sense repetitive DNA to the ends of linear chromosomes.

Telomerase is an enzyme that has a protein part and an RNA part. The RNA part of telomerase has a nucleotide sequence that can base-pair with the sequences in the telomere. When the RNA base-pairs with the sequence at the ends of the chromosome, it provides a template for the synthesis of new telomere repeats. The protein component of telomerase is a reverse transcriptase, an enzyme that can make DNA copies from RNA templates. Telomerase can copy the sequence of the RNA bound to the end of the chromosome to make DNA copies of the telomere sequence.

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