Why not a DNA made of A&T; only? Due: Mar 28, 2018 11:59 PM Last Submission: Non

Question

Why not a DNA made of A&T; only? Due: Mar 28, 2018 11:59 PM Last Submission: None In class we discussed how the G-C pairs easily explain the need for DNA strands to align in anti-parallel orientation for the base pairing to occur. Flipping either base prevented the proper H-bonds to form between the nitrogenous bases. But let's now take a look at the A-T pair in the image. It would appear that given thymidine's symmetry, you could flip the bases and two H-bonds would still form between either anti-parallel (5-3' ll 3'-5) or parallel (5-3' Il 5'-3') helices

Explanation / Answer

All nitrogenous basepair have their specific qualities and role in the body. All react with particular enzymes and give different products which are very important for a healthy human. So if evolution adapted only two nitrogenous bases then our body would not be able to work properly like it does now. Still, the DNA structure is the major topic to study but then also all basepairs have their individual roles which cannot be replaced.

In evolution uracil replaced by thymine during the evolution of DNA from RNA because cytosine easily converted in uracil by deaminase enzyme that can form complementary with adenine during replication resulting GC basepair converted in AU basepair.

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