1. Which of the following has to do with transcription? A. Promoters B. RNA Poly
ID: 217590 • Letter: 1
Question
1. Which of the following has to do with transcription?
A. Promoters B. RNA Polymerase C. Death cap mushroom – Amanita phalloides D. All of the above
2. The mRNA transcript is more similar to:
A. The template strand B. The non-template strand
3. The difference between the mRNA transcript and the non-template strand is:
A. They have different polarity B. The sequences are complementary (vs. identical) C. The mRNA has U instead of T D. All of the above
4. Substrates in transcription:
A. Could include Adenine B. Could include Thymine C. Have a deoxyribose sugar D. Lack –OH at 2’ on the sugar
5.A splice site is mutated so that splicing does not occur. What is the expected effect on the mature mRNA?
A. The mRNA would be the same length, but would encode a different protein B. The mRNA would be shorter than normal C. The mRNA would be longer than normal
Explanation / Answer
Answer:
1). B. RNA Polymerase
Explanation: Amanatin is a toxin found in the death cap mushroom, Amanita phalloides.It inihibits transcription by blocking RNA polymerase.
2). B. The non-template strand
Explanation:
The mRNA is complementary to template DNA and identical with non-template DNA.
3). C. The mRNA has U instead of T
Explanation:
The sequence of the mRNA is complementary to the template strand and identical to the coding strand with U substituted for T
4). A. Could include Adenine
Explanation:
Could include Thymine & deoxyribose sugar (lack –OH at 2’ on the sugar) are found in DNA.
5). A. The mRNA would be the same length, but would encode a different protein
Explanation:
A splice site mutation is a genetic mutation that inserts, deletes or changes a number of nucleotides in the specific site at which splicing takes place during the processing of precursor messenger RNA into mature messenger RNA. Splice site consensus sequences that drive exon recognition are located at the very termini of introns. The deletion of the splicing site results in one or more introns remaining in mature mRNA and may lead to the production of abnormal proteins
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