1. Calculate the volume of O2 in ml bound to 1 gram of hemoglobin if pO2 is 110

Question

1. Calculate the volume of O2 in ml bound to 1 gram of hemoglobin if pO2 is 110 mmHg Some tips: First, write out the balanced equation for the reaction between O2 and Hb,at this pressure. Then, use knowledge of general chemistry and the ideal gas law to solve the problem starting with g Hb all the way to ml O2 This problem will take several steps. You can assume standard atmospheric pressure at sea level and typical resting body temperature. You can google the following: the ideal gas constant, the standard pressure, the typical resting core body temperature, and the molecular weight of Hb, Make sure you use the right units and the proper ideal gas constant with the right units! The rest of this will require you to calculate and show your work. It is your responsibility to obtain the right values Hint: What am I? 2. Next, find the following values in the Saladin textbook: Midpoint value for your sex's hemoglobin concentration: Midpoint value for your sex's blood Then, calculate the typical total blood hemoglobin content (grams) for your sex using the obtained values from the textbook. Then, determine total blood O2 content (volume in mL; assume Hb saturation corresponds to your pO2 listed above) using your calculated (not googled!) values for mL O2/g Hb and g Hb in the blood.

Explanation / Answer

1. 1.39 ml of oxygen in one gram of hemoglobin

2. Midpoint value for your sex (female) hemoglobin concentration : 14 g/dL

Midpoint value for female's blood volume: 5 L

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