Which of the following is NOT associated with canonical G-protein coupled recept

Question

Which of the following is NOT associated with canonical G-protein coupled receptor (GPCR) signaling? Ras monomeric GTPase gets activated O Replacement of GDP with GTP causes dissociation of the subunit from the subunits of a heterotrimeric G-protein Adenylyl cyclase is activated, causing an increase in production of cyclic AMP (CAMP) Second messengers are released leading to signal amplification. O The receptor becomes phosphorylated and gets inactivated through binding with an inhibitory MUt siri.

Explanation / Answer

Second messenger are released leading to signal amplification is not associated with canonical G - protein coupled receptor (GPCR) signalling.

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