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2. In the pre-operating waiting area, an anesthesiologist administers clonidine,

ID: 212231 • Letter: 2

Question

2. In the pre-operating waiting area, an anesthesiologist administers clonidine, an anxiolytic (decreases anxiety) to a patient waiting for a hemicolectomy. Which type of adrenergic receptor does clonidine activate to exert a decrease in anxiety? 3. Consider the following microcircuit: C/B (A and B are pyramidal neurons, while C and D are interneurons). Clonidine is now applied to a neuronal preparation with this microcircuit. It specifically targets receptors in D. Is neuron B more or less excitable now? Less ex citable 4 What is the difference between cocaine and amphetamine's mechanism of increasing

Explanation / Answer

It stimulate the alpha adrenoceptor in brain stem. This action results in reduced sympathetic outflow from Central nervous system and reduction in renal vascular resistance , peripheral resistance, heart beat, blood pressure and overall anxiety

Less excitable

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