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Problem 2 - (8 pts) A protein called titin is found in our muscles. Titin has bo

ID: 211505 • Letter: P

Question

Problem 2 - (8 pts) A protein called titin is found in our muscles. Titin has both strength and elasticity. The figure below shows the x-ray structure of the binding domain between two titin proteins (A and B) Z2 Z1 Z2 Z1 1) What secondary structure dominates this binding domain? (short answer, 2 pts) 2) If this protein complex was pulled as indicated by the two arrows, what would happen at the molecular level? (4 pts) 3) As compared to a single alpha-helix with a similar end-to-end length when folded which protein would have greater extension length (unravel length) when pulled? (2 pt)

Explanation / Answer

1) anti-parallel beta-sheets

2) Bonds/ interactions which were holding the 2 proteins would be broken

3)the right side protein would have a higher extension length.

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