40 mv 4. (2 pts each) For a given neuron, you determine that the equilibrium pot
ID: 210126 • Letter: 4
Question
40 mv 4. (2 pts each) For a given neuron, you determine that the equilibrium potential of Cr is -40 mv. a. Is the Cl concentration higher inside or outside the cell? b. Which direction would cr flow if you set the membrane potential to 0 ? Write in (into the cell) or out (out of the cell) c. Which direction would Cl flow if you set the membrane potential to -80 mV? Write in (into the cell) or out (out of the cell) You identify a drug that shifts the voltage dependence of voltage-gated sodium channels, sing them to open at a higher (less negative) membrane potential than usual.Explanation / Answer
Ans A) Chloride ion will enter into the neuron.
Explaination - Chloride ion concentration is higher in the outside of the neuron cell while the concentration of chloride is less inside the neuron. As the membrane potential is -40 mV and the neuron can become hyperpolarised in response to a stimuli. So, more chloride ion can enter into the neuron through specific channels and take to the neuron to the hyper-polarised state. until its channel are closed.
Ans B) Chloride ion will move out of the neuron.
Explaination- When the membrane potential of neuron is set to 0 mV that is the neuron is in depolarised state. then the Cl- ions will moves out of the cell through the specific transporter proteins or channels. Depolarisation of neuron occur by the opening of the positive ions channels which enter into the neuron and simultaneously exit of negative ions from the neuron.
Ans C) No movement of ions will occur at -80 mV.
Explanation- No amount of cholide ion will enter into the neuron as the neuron is hyperpolarised and can only release its negative ion to become de-polarised. No Chloride ions will moves in the cell if membrane potential is made -80 mV.
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