You have discovered a membrane transporter that mediates the import of leucine i

Question

You have discovered a membrane transporter that mediates the import of leucine into the cytosol from the bloodstream. It utilizes the electrochemical gradient of Cl- to pump leucine uphill the concentration gradient. You replaced blood with an isotonic solution that contains the equal concentration of leucine as in the bloostream, but without any Cl-. What will happen?

A. the concentration of leucine inside and outside of cells will become the same

B. Leucine doesnt need an active transport since its side chaim is non polar

C. Leucine will be actively transported out from the cytosol

D. Cl- will be actively imported while leucine gets exported

Explanation / Answer

Leucine doesnt need an active transport since its side chaim is non polar. leucine contains an -amino group (which is in the protonated NH3+ form under biological conditions), an -carboxylic acid group (which is in the deprotonated COO form under biological conditions), and a side chain isobutyl group, making it a non-polar aliphatic amino acid.

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