1. The table below summarizes four examples of different sets of relative fitnes
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Question
1. The table below summarizes four examples of different sets of relative fitness values for three genotypes at a given locus. WAA VW Example 1 0.4 Example 21.0 Example 3 10 Example 4 0.5 0.7 0.6 0.3 0.5 For each example, what would be the eventual outcome of selection (i.e., fixation of "A" allele, fixation of "a" allele, or a balanced polymorphism)? In answering this question, you can ignore any effects of genetic drift, mutation, and migration. But do not assume that the "A" allele is dominant. If your answer would depend on the current allele frequencies in the population, provide separate answers for when "A" is common (p >> 0.5) and for when "A" is rare (pExplanation / Answer
Geometric mean fitness for: W(AA) is =(0.4*1.0*1.0*0.5)^1/4=0.668
for : W(Aa)= (0.7*1.0*0.3*1.0)^1/4= 0.676
for :W(aa)= (0.5*1.0*0.6*1.0)^1/4= 0.739
(all else equal, natural selection favors alleles with a smaller variance in fitness through time.)
Analysis shows that the allele that ultimately predominates in a population is the one with the highest geometric mean fitness through time. So with above data given W(aa) will dominate in population and hence outcome of the selection.
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