(d) NADP* 27. Direction of Oxidation-Reduction Reactions Which of the following

Question

(d) NADP* 27. Direction of Oxidation-Reduction Reactions Which of the following reactions would you expect to proceed in the direction shown, under standard conditions, in the presence of the appropriate enzymes? (a) Malate + NAD+ oxaloacetate + NADH + H+ (b) Acetoacetate + NADH + H+ -hydroxybutyrate + NAD+ (c) Pyruvate + NADH + H+-lactate + NAD' (d) Pyruvate + -hydroxybutyrate- lactate + acetoacetate (e) Malate + pyruvate (f) Acetaldehyde+ succinate- ethanol + fumarate oxaloacetate + lactate or an jun Data Analysis Problem cule F1 F2 20 F3 F4 FS

Explanation / Answer

The first reactin shown , in which Malate and NAD+ are reacting and forming Oxaloacetate and NADH and H+, proceed in the direction shown. This is a reaction in the TCA cycle of cellular respiration which takes place inside mitochondria. Oxaloacetate produced goes back again into the cyclic reaction phase. The enzyme which accelerates this conversion process is Malate dehydrogenase.

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