Osman, Cell Bio 3201, SPRING 2018 (d) larger amino acids in the active site decr

Question

Osman, Cell Bio 3201, SPRING 2018 (d) larger amino acids in the active site decreases the affinity for substrate 4-55 Match the general type of biochemical reaction catalyzed in the left column with the class of enzyme listed in the column on the right _ removes a phosphate group from a molecule A-ATPase hydrolyzes ATP B. polymerase C. ligase D, kinase E. isomerase F. nuclease hydrolyzes bonds between nucleotides adds phosphate groups to molecules catalyzes reactions in which one molecule is oxidized and another is reduced -hydrolyzes peptide bonds -joins two ends of DNA together -catalyzes the synthesis of polymers such as H. protease I. phosphatase RNA and DNA -rearranges bonds within a single molecule For some proteins, small molecules are integral to their structure and function. Enzymes can synthesize some of these small molecules, whereas others, called vitamins, must be ingested in the food we eat. Which of the following molecules is not classified as a vitamin but does require the ingestion of a vitamin for its production? (a) retinal 4-56 (c) biotin (d) heme (c) zinc For each of the following sentences, fill in the blanks with the best word or phrase selected from the list below. Not all words or phrases will be used; each word or phrase should be used only once. 4-57 Any substance that will bind to a protein is known as its-- Enzymes bind their enzyme hexokinase is so specific that it reacts with only one of the two at the The lowering the for the formation of a , because they provide conditions favorable intermediate called the Once the reaction is completed, the enzyme releases the of the reaction. activation energy active site free energy isomers ligand products substrates transition state Page 15 of 20

Explanation / Answer

1. Removes a phosphate group from a molecule: Phosphatase(A phosphatase removes a phosphate group by a hydrolysis reaction, producing inorganic phosphate)

2. Hydroluzes ATP: ATPase

3. hydrolyzes bonds between nucleotides: Nucleases

4. Adds phosphate group to the molecule: Kinase

5. Catalyzes reactions in which one molecule is oxidized and other is reduced: Oxido-reductase

6. Hydrolyze peptide bond: Protease

7. Joins two ends of DNA together: Ligase

8. Catalyzed the synthesis of polymers: RNA polymerase

9. Rearranges bonds within a single molecule: isomerase

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