Which of the following orders of events occurs routinely during cytokine signali

Question

Which of the following orders of events occurs routinely during cytokine signaling? (1 point) O Cytokine receptor >receptor dimerization > Serine/threonine (S/T-phosphorylation>STATtranscription. OCytokine receptor >conformational change of receptor> S/T-phosphorylation>SMADtranscription. O Cytokine receptor >receptor endocytosis >STAT>SMADtranscription. O Cytokine receptor >conformational change of receptor >tyrosine-phosphorylation > STAT>transcription. Cytokine receptor >conformational change of receptor > S/T-phosphorylation >STAT>transcription.

Explanation / Answer

The answer is- Cytokine receptor > conformational change of the receptor > tyrosine phosphorylation > STAT > transcription.

Cytokines are low molecular weight (30kd) soluble protein or glycoprotein. Cytokine signaling occurs in the following pathway-

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