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Proofreading 1. You are given the following short segment of DNA double helix. S

ID: 199767 • Letter: P

Question

Proofreading

1. You are given the following short segment of DNA double helix. Strand 1 – 5’ A – A – T – T – C – G – C – T – A – G – C – 3’ Strand 2 - 3’ T – T – A – A – G – C – G – A – T – C – G – 5’ (anti-parallel) Give the compliment for each strand and explain how the new 2 short segments of DNA double helix will appear.

2. After several generations of replication, the above strand of DNA appears as such immediately after being copied. Strand 1 – 5’ A – A – T – T – C – G – C – T – A – G – C – 3’ Strand 2 - 3’ T – T – A – A – G – G – C – T – T – C – G – 5’ (anti-parallel) Describe the concern here and what will be done to correct the problem.

Explanation / Answer

Compliment for 1- 3’ TTAAGCGATCG5’

For 2- 5’ AATTCGCTAGC3’

The short segment occur by replication of dna strands

2- there is one base pair defect in the chain which can be corrected by dna repair by dna polymerase enzyme .