4. Hemophilia was called \"the royal disease\" because many of the European roya

Question

4. Hemophilia was called "the royal disease" because many of the European royal families had members afflicted with hemophilia. Hemophilia is a sex-linked, recessive, X-chromosome disorder. It was known that Queen Victoria was unaffected but was a carrier of the hemophilia gene (Xix>).Suppose Queen Victoria's husband, Prince Albert, was affected with hemophilia (X Y.. What is the percent probability that Queen Victoria and Prince Albert will have two affected females and an unaffected son? 5. Red-green color blindness is an X-linked recessive trait in humans. Polydactyly (extra fingers and toes) is an autosomal dominant trait. Martha has normal fingers and toes and normal color vision. Her mother is normal in all respects, but her father is color blind and polydactylous. Bill is color blind and polydactylous. His mother has normal color vision and normal fingers and toes. If Bill and Martha marry, what proportions of ehildren with specific phenotypes would they be expected to produce?

Explanation / Answer

There is a 50% chance that the daughter will be affected and a 50% chance the daughter will be just a cariier.

In case of the son too there is a 25% chance the son will be affected hence there is a 75% chance that the son will be unaffected

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