Ls4203_midsem_2016 please answer only question no.1. (2+3=5 marks) Time: 10 AM t
ID: 196742 • Letter: L
Question
Ls4203_midsem_2016
please answer only question no.1. (2+3=5 marks)
Time: 10 AM to 10:55 AM Answer any four: I. How Isozymes give advantages in metabolism? Explain with example? How Insulin and Glucagon regulate the glycolysis and gluconeogenesis? 2+3-5 2. What will be the pathophysiological effecet of loss of function mutation of elycogen phosphorylase? How C-AMP regulate the activity of Glycogen phosphorylase? How blood glucose levels regulate the activity of Glycogen phosphorylase? 2+1.5+ 1.5-5 3. What is the function of Pyruvate Dehydrogenase complex (PDH)? Describe the role of each cofactors involved in the reaction catalyzed by the pyruvate dehydrogenase complex. What are the regulations of activity of pyruvate dehydrogenase complex? 1+2+2#5 4. Why animal could not survive with only on sneetate as soie carbon sourec? How plant and microbes can survive with acetate as sole carhon source? In aduli animat if the food is only lipid: what will be the consequences? What is role of Perosisome in fatty acid oxidation? 1+2+1+1-5 5. Explain why referring to the Calvan gycte as the "dad reactions ot photosynthesis isExplanation / Answer
A case of an isozyme is glucokinase, a variation of hexokinase which isn't repressed by glucose 6-phosphate. Its distinctive regulatory highlights and lower liking for glucose (contrasted with different hexokinases), enables it to serve extraordinary works in cells of particular organs, for example,
insulin controls glycolysis in 2 ways
1. Insulin actuates phosphodiesterase which debases cAMP and inactivates PKA, PKA can't phosphorylate the kinase part of PFK-2 so F26BP is made.
2. Insulin actuates phosphoprotein phosphatase which dephosphorylates the kinase area of PFK-2 so F26BP is made. Both promptly expanded glycolysis
Gluconeogenesis
Glucagon increased gluconeogenesis from propionate and lactate but not from glycerol.
Glucagon effects on gluconeogenesis.
The data indicate that, in the neonatal bovine liver, glucagon acts on a process common to lactate and propionate to increase gluconeogenesis, and insulin opposes these effects on gluconeogenesis from propionate but not lactate.
Related Questions
Navigate
Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.