2 2 5 6 2 5 6 The pedigree above is for an autosomal recessive trait. Questions

Question

2 2 5 6 2 5 6 The pedigree above is for an autosomal recessive trait. Questions 29- 32 below are based on this pedigree. --29) what is the probable genotype(s) for individual 1-1? a) Homozygous dominant b) Heterozygous c) Homozygous recessive d) Hemizygous dominant e) Hemizygous recessive 30) What is the probability that individual III-2 is a carrier of the recessive allele? 31) What is the probability that individual IV- 4 is a carrier of the recessive allele? 32) What is the probability that individual IV-4 and IV-5 will have an affected child?

Explanation / Answer

29. Genotype of I-1 is

B. Heterozygous.

30. Probability for III-2 being carrier is 100%. This is because one of his parent ( father) is affected and he has received ne mutant copy of allele from his father. Therefore his genotype is heterozygous.

31. Probability of individual IV-4 being carrier is 50%.

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