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PART 1: METABOLIC PATHWAYS Metabolic pathways are a series of chemical reactions

ID: 195108 • Letter: P

Question

PART 1: METABOLIC PATHWAYS Metabolic pathways are a series of chemical reactions that occur in living cells. A pathway can be thought of as a linked set of isolated chemical reactions (each with a set of reac- tants and products) for which one or more oft the products of one reaction become the reac. hand for "substra Aside: Since biological reactions are often catalyzed by enzymes we often casually re- fer to the chemical reactants as "substrates of the reaction"-keep in mind that this is short- tes of the enzyme catalyzed reaction tants for the next in the chain. We often view these pathways from the standpoint of an ini- tial chemical (metabolite) that is acted upon through a sequence of chemical reactions. In each step of this pathway, energy and mass are transferred to and/or from the original metabolite to transform it into a new molecule. In biology, each of the individual reactions in a metabolic pathway is often (but not always) catalyzed by an enzyme. Below is an example from a metabolic pathway. We often use some shorthand to describe the pathways like these as follows: "Metabolite A is converted to B, which is converted to C, which is then converted to D." Notice that we have focused the attention on the components in the pathway whose molecular structures are shown and that we do not explicitly say anything about the other components of the reactions labeled in smaller font or abbreviated by numbers (these are equally important to understanding the pathway as the text in large font). In this exercise you will focus on reading and describing these types of diagrams FULLY. or 0 2 3 HCOH HCOH HCOH NAD NADH H,COP ADP ATP H,Co e 1·The numbers in the pathway above represent enzymes. List the reactants and products of the reaction catalyzed by enzyme 1. Reactants Products 2. List the reactants and products of reaction 2. Reactants Products

Explanation / Answer

Answer
In this question the reaction shows the second phase of glycolysis, In this reaction theirs is generation of energy molecule in the form of ATP.
1)   The given molecule (Reactant) is Glyceraldehyde-3- phosphate which undergo oxidation in which the H+ ion is removed from the first carbon of this molecule with the help of
Enzyme-1 Glyceraldehyde – 3- phosphate dehydrogenase. Also NAD+ is converted into NADH.The product generated from the reaction is 1,3 bisphosphoglycerate.
2)   The given molecule (Reactant) is 1,3 bisphosphoglycerate which undergo reduction in which the P+ ion is removed from the first carbon of this molecule with the help of
Enzyme-2 Phoshoglycerate kinase. Also ADP+ is converted into ATP.The product generated from the reaction is 3-bisphosphoglycerate.