4. A \"sequence logo” is similar to a consensus sequence but also indicates the

Question

4. A "sequence logo” is similar to a consensus sequence but also indicates the frequency of the most common nucleotide at each position. In the example below, the A at position 5 is tall, indicating that it is found in most examples of this motif. In contrast, the A at position 7 is shorter, indicating that many instances of the motif have other nucleotides at this position. Explain why it is useful to have the additional information in the sequence logo compared to a consensus sequence. LE AAÇA, ITC, ! ! ! ! -

Explanation / Answer

a consensus displays only conservation information, and not explicitly the frequency information of each nucleotide or amino acid at each position. Instead of a stack made of several characters, denoting the relative frequency of each character, the consensus depicts the degree of conservation of each position using the height of the consensus character at that position.

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