T-Mobile 9:21 AM Quiz 2: Attempt 1 Question 6 1 out of 1 points \"A researcher w
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T-Mobile 9:21 AM Quiz 2: Attempt 1 Question 6 1 out of 1 points "A researcher wants to identify genes associated with alcohol abuse. She uses a chemical to mutagenize a population of fruitflies. She then treats the flies with alcohol vapors. Wild-type flies eventually fall over when treated with these vapors, and she identifies flies that fall over even faster than wild-type flies when exposed to alcohol. Once she identifies these flies, she analyzes their genomes to determine which genes have been mutated in these flies and might be associated with lower tolerance to alcohol. This is an example of" Question 7 1 out of 1 points Which of the following statement(s) accurately describe a protein domain? Question 8 1 out of 1 points The chaperone Hsp60 recognizes potentially misfolded proteins by attracting exposed hydrophobic regions of proteins. Why do you think this is the case?Explanation / Answer
Q.7
Ans: Protein Domain: Proteins domains are distinct functional and / or structural units in a protein.
They are responsible for a particular functions or interaction , contributing to the overall role of a protein. There is currently 53 million protein domain.
Q.8: The Hsp60 heat shock proteins are abundant in prokaryotes and eukaryotes and are required 8n folding , translocation and assembly of native proteins.
Hsp60 acts as molecular cheperone with other cheperone to fulfill their specific functions.
Hsp60 are chracterized by their ability to identify protein with abnormally exposed hydrophobic residue and to form stable inactive aggregates after association.
SHsp60 show an intrinsic ATPase activity implaying an Atp- driven increase in the free energy of misfolded and aggregate d substrate molecules.Hsp60 is critically involved in the replication and transmission of mitochondrial DNA with high specificity for template strand of a positive origin or mtDNA replication.
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