Spartan Village East Lansing MI Vail Ski Resort Vail, CO ambient pO2 tracheal pO

Question

Spartan Village East Lansing MI Vail Ski Resort Vail, CO ambient pO2 tracheal pO2 alveolar pO2 arterial pO2 159 mm Hg 149 105 100 95 mm Hg 86 50 45 nformation on oxygen pressures are provided above for Michigan and Colorado. You leave East Lansing or a holiday skiing trip. Two days after arriving at Vail, the best prediction for [2,3-diphosphoglycerate] nd Pso for your body is: 12.3-diphosphoglyceratel Ps(mmHg) A) B) C) D) E) The symbols, t, andrepresent increase, decrease, and remain the same, relative to Michigan.

Explanation / Answer

Answer - A

Vail has low O2 concentration compare to the MI. After returing to the Vali he is going to affect by the altitude sickness due to low O2 concentration in the surrounding. To adjust that 2,3-bisphosphoglycerate (2,3-BPG) Increases and binds to hemoglobin and stabilizes low O2 affinity T state.It leads to decreasing hemoglobin affinity for O2 and increaing O2 unloading.

P50 is PO2 at which hemoglobin is 50% saturated. Increasing P50 is decreasing PO2 at which hemoglobin is 50% saturated.

This is Bohr's effect right shift example.

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