3. Which of the following statements are TRUE about Toll-ike receptors (TLRs)? a

Question

3. Which of the following statements are TRUE about Toll-ike receptors (TLRs)? a. They may be found as membrane receptors on pathogens b. They may be found as membrane receptors in the endosomal membrane of cells c. They may be found as soluble receptors in the cytosol of cells d. They can react to every possible structural detail of microorganisms. e. a and b 4. Which of the following is an example of intrinsic immunity? a. natural killer cells b. anti-microbial peptides in skin c antibodies d. plasma cells e. CD8 T cells

Explanation / Answer

Answer: B and D are correct

Explanation

B: Some TLRs like TLR3, 7, 8, and 9 are anchored in endosomal membranes. They are found towards cytosol and help pathogens degradation in the cell.

D: They are also termed as pattern recognition receptor (PRR). These recognize those molecules which are common in pathogens but different from host molecules. These are also called pathogen-associated molecular patterns (PAMPs).

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