A. The cells in your body receivehalf their chromosomes from your father and one

Question

A. The cells in your body receivehalf their chromosomes from your father and one half of theirchromosomes from your mother. So for each pair of homologouschromosomes one will be a maternal chromosome and one will be apaternal chromosome.. During meiosis when the haploid gametes areformed, each member of the pair but not both ends up in a gamete.This is the principle of segregation.1. For humans (N =23) how manypossible combinations of maternal and paternal chromosomes arethere? Show your reasoning. Hint: are we dealingwith ordered or unordered events here?

B, How many of thecombinations from part A involve 10 maternal chromosomes and 13paternal chromosomes? Hint are we dealing with an ordered orunordered event here?

Explanation / Answer

1. For humans (N =23) how many possible combinations ofmaternal and paternal chromosomes are there?

For any single pair of chromosomeseither the gamete has a maternal chromosome or a paternalchromosome, so there are two possibilities for any single pair ofchromosomes. Since we have 23 pairs of homologous chromosomes thereare 223 possible combinations of maternal Vs paternalchromosomes in the gametes.

2. How many of these combinations involve 10 maternalchromosomes and 13 paternal chromosomes?

We want the total number of orderedcombinations involving 10 maternal and 13 paternal chromosomes. Souse the formula:

N!/[(M!)(N-M)!] where N = 23 and M= 13

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