A. The cells in your body receive half their chromosomes from your father and on

Question

A. The cells in your body receive half their chromosomes from your father and one half of their chromosomes from your mother. So for each pair of homologous chromosomes one will be a maternal chromosome and one will be a paternal chromosome.. During meiosis when the haploid gametes are formed, each member of the pair but not both ends up in a gamete. This is the principle of segregation.1. For humans (N =23) how many possible combinations of maternal and paternal chromosomes are there? Show your reasoning.

B, How many of the combinations from part A involve 10 maternal chromosomes and 13 paternal chromosomes? Hint are we dealing with an ordered or unordered event here?

Activity 5

Recall that DNA is made from a sequence of four nucleotides that differ in terms of which nitrogen base A,T,G,C is present in each nucleotide. Suppose you have a region of DNA which is 100 nucleotides long. How many possible nucleotide sequences are there for this region of DNA?

Explanation / Answer

A 1. The Law of Segregation says that every human being contains two alleles for each triat. These alleles segregate during meiosis such that each gamete contains onel of the allele.

2. The offsprings receives one allele for each triat from each parent.

3. The Law of Independent a Assortment states that chromosomes are randomly sorted from all possible maternal and paternal chromosomes.

4. In eukaryotic organisms during meiotic prophase-1 produces a gamete with a mixture of the organism's chromosomes.

5. Because zygotes end up with a random mix from either parent, chromosomes are assorted independently.

6. Such zygote can end up with any combination of maternal or paternal chromosomes.

7. For human gamets with 23 pairs of chromosomes, number of possibilities is 223 or 8,388,608 possible combinations.

B. Possibilites of combinations involves 10 maternal chromsomes are 210 or 1024 possible combinations of eggs(femal gamets). Similarly 13 paternal chromosomes are 213 or 8192 possible combinations of sperms (male gamets).

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