Arrange the following steps in correct series of the Serine Protease Mechanism:

ID: 182372 • Letter: A

Question

a. His57 stabilized by a LBHB

b. Carboxyl product leaves and completes the serine protease mechanism

c. the formation of the covalent ES complex involves general base catalysis by His57

d. the amino product departs, making room for an entering water molecule

e. nucleophilic attack by water is facilitated by His57, acting as a general base

f. collapse of the tetrahedral intermediate releases the amino product

g. binding of a substrate

h. collapse of the tetrahedral intermediate cleaves the covalent intermediate, releasing the carboxyl product

The step involved in the serine protease mechanism are:

Serine proteses serves various functions in the digestion ,blood coagulation,immune response and reproduction.

serine proteases cleave peptide bonds in proteins.

Catalytic Triad plays an important role in cleaving the proteases..

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