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A mutant plant with white flowers exists that backs red pigment, normally made b

ID: 181058 • Letter: A

Question

A mutant plant with white flowers exists that backs red pigment, normally made by enzyme P, Indeed the petal tissue lacks all detectable activity for enzyme P. Despite the lack of enzyme activity, a study of homozygous mutant cells using antibodies against the wild-type enzyme demonstrated that the cells homozygous for the mutations still had the enzyme (i.e., the antibody showed the presence of the enzyme) Which statement could explain these results? The mutant had another gene the researcher was not aware of which produced an enzyme that could function like the mutated enzyme. The mutant cells likely had large scale chromosomal mutations that resulted in the expression of some gene similar to the gene for enzymes P. The mutant allele must have had a nonsense mutation that resulted in complete formation of a non-functioning enzyme. The mutant allele must only have mutations that simply located enzyme function yet the enzyme would still bind to the antibody. Note of the answers are correct.

Explanation / Answer

Answer is C: The mutant allele must have had a nonsense mutation that resulted in complete formation of a non-functioning enzyme.

All enzymes are protein in nature. Mutation is the change in nucleotide sequence of DNA. Nonsense mutation is a point mutation in the sequence of DNA and changes an amino acid to a stop codon ends up with the premature termination of translation. The enzyme’s function can be destroyed with this type of mutation but still it has the same immunological property.

Enzymes have the active site which enables the substrate to bind to it and produces the products. Any substitution of the important amino acids in the active site will not affect the overall size and shape of the enzyme but instead it loses its enzymatic activity.

Answer is C: The mutant allele must have had a nonsense mutation that resulted in complete formation of a non-functioning enzyme.

All enzymes are protein in nature. Mutation is the change in nucleotide sequence of DNA. Nonsense mutation is a point mutation in the sequence of DNA and changes an amino acid to a stop codon ends up with the premature termination of translation. The enzyme’s function can be destroyed with this type of mutation but still it has the same immunological property.

Enzymes have the active site which enables the substrate to bind to it and produces the products. Any substitution of the important amino acids in the active site will not affect the overall size and shape of the enzyme but instead it loses its enzymatic activity.

Answer is C: The mutant allele must have had a nonsense mutation that resulted in complete formation of a non-functioning enzyme.

All enzymes are protein in nature. Mutation is the change in nucleotide sequence of DNA. Nonsense mutation is a point mutation in the sequence of DNA and changes an amino acid to a stop codon ends up with the premature termination of translation. The enzyme’s function can be destroyed with this type of mutation but still it has the same immunological property.

Enzymes have the active site which enables the substrate to bind to it and produces the products. Any substitution of the important amino acids in the active site will not affect the overall size and shape of the enzyme but instead it loses its enzymatic activity.

Answer is C: The mutant allele must have had a nonsense mutation that resulted in complete formation of a non-functioning enzyme.

All enzymes are protein in nature. Mutation is the change in nucleotide sequence of DNA. Nonsense mutation is a point mutation in the sequence of DNA and changes an amino acid to a stop codon ends up with the premature termination of translation. The enzyme’s function can be destroyed with this type of mutation but still it has the same immunological property.

Enzymes have the active site which enables the substrate to bind to it and produces the products. Any substitution of the important amino acids in the active site will not affect the overall size and shape of the enzyme but instead it loses its enzymatic activity.

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