Which of the the following statements about the function of regulatory RNAs in X
ID: 180339 • Letter: W
Question
Which of the the following statements about the function of regulatory RNAs in X-chromosome activation is NOT true? Q. 13) which of the following statements about the function of regulatory RNAs in x- chromosome inactivation is NOT true? a) Xist RNAs produced by one x-chromosome can initiate inactivation of genes located on the ther X-chromosome (they are trans-acting regulators). the recruitment b) Xist coats the X-chromosome from which it was transcribed, which leads to of other factors that modify and condense the chromatin. the rest of the genome. c) Inactivated X-chromosomes are much less acetylated than active X chromosomes. d) Inactivated X-chromosomes are condensed compare with theExplanation / Answer
ANSWER A
Xist produced by one X chromosome can initiate the inactivation of other X chromosome ( is the wrong statement)
EXPLAINTION
Central to XCI is the long non-coding RNA Xist, which is highly and specifically expressed from the inactive X chromosome. Xist covers the X chromosome in cis and triggers genetic silencing, but its working mechanism remains elusive
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