Insulin binding to its receptor on the surface of adipocytes activates which of

Question

Insulin binding to its receptor on the surface of adipocytes activates which of the following responses?

Answers:

Insulin receptor activates IRS-1 by phosphorylation to relocate GLUT4 to the plasma membrane and provides increased substrate for hexokinase.

Insulin signals by activating heterotrimeric G-proteins which ultimately increase cAMP levels causing the relocation of GLUT4 from intracellular vesicle to the plasma membrane.

Insulin activates the relocation of GLUT2 and glucokinase to the cell surface to increase glucose uptake.

Insulin activates IRS-1 to increase the availability of the high affinity transporter, GLUT1, on the cell surface for increased glucose uptake.

Insulin binding to its receptor on the surface of adipocytes activates which of the following responses?

Answers:

Insulin receptor activates IRS-1 by phosphorylation to relocate GLUT4 to the plasma membrane and provides increased substrate for hexokinase.

Insulin signals by activating heterotrimeric G-proteins which ultimately increase cAMP levels causing the relocation of GLUT4 from intracellular vesicle to the plasma membrane.

Insulin activates the relocation of GLUT2 and glucokinase to the cell surface to increase glucose uptake.

Insulin activates IRS-1 to increase the availability of the high affinity transporter, GLUT1, on the cell surface for increased glucose uptake.

Explanation / Answer

Answer:Option 1

Insulin binding to its receptor on the surface of adipocytes activates IRS-1 by phosphorylation to relocate GLUT4 to the plasma membrane and provides increased substrate for hexokinase

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